Alpelisib Hagati 4-Methyl-2- (1,1,1-trifluoro-2-dimethyl-2-ethyl) pyridine CAS OYA.1378865-93-0

CAS nimero 1378865-93-0, 4-methyl-2- (1,1,1-trifluoro-2-dimethyl-2-ethyl) pyridine ikomatanyirizwa hamwe ikageragezwa kugirango ihuze ubuziranenge nubuziranenge.Ifite uruhare runini muri synthesis ya Alpelisib, ubuvuzi bugenewe abarwayi bafite kanseri y'ibere yateye imbere cyangwa ibibyimba bikomeye bifite ihinduka rya PIK3CA.

Hagati ya Alpelisib ikora nk'urwego rwo kubaka synthèse ya Alpelisib, ituma habaho gukora imiti yerekanye akamaro gakomeye mubigeragezo byamavuriro.Imiterere yimiti nyayo yabahuza bacu ituma ihuza kandi ikora neza mugihe cya synthesis, bigira uruhare mubisukuye byinshi nimbaraga za farumasi yanyuma.

4-Methyl-2- (1,1,1-trifluoro-2-dimethyl-2-ethyl) pyridine intermedia ni igice cyingenzi muri synthesis ya chimique ya Alpelisib kandi ni urufunguzo rwingenzi mubikorwa byose byakozwe.Nuburyo bwuzuye bwa molekuline nuburemere, byateguwe kugirango byuzuze ibisabwa bikenewe mu gukora imiti, byemeza ko bihoraho kandi byizewe mu musaruro wa Alpelisib.